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Creators/Authors contains: "Hausner, Christian"

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  1. ; ; ; ; ; ; ; ; ; ; et al (, Communications Biology)
    Current methods for producing cardiomyocytes from human induced pluripotent stem cells (hiPSCs) using 2D monolayer differentiation are often hampered by batch-to-batch variability and inef!cient puri!cation processes. Here, we introduce CM-AI, a novel arti!cial intelligence-guided laser cell processing platform designed for rapid, label-free puri!cation of hiPSC-derived cardiomyocytes (hiPSC-CMs). This approach signi!cantly reduces processing time without the need for chronic metabolic selection or antibody-based sorting. By integrating real-time cellular morphology analysis and targeted laser ablation, CM-AI selectively removes non-cardiomyocyte populations with high precision. This streamlined process preserves cardiomyocyte viability and function, offering a scalable and ef!cient solution for cardiac regenerative medicine, disease modeling, and drug disco 
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    Free, publicly-accessible full text available December 1, 2026